We protect
the genome.
Genome instability is the cause of cancer and a major driver of aging
Mutations drive cells toward dividing rapidly and uncontrollably, leading to oncogenesis
As we age, DNA damage leads to epigenetic entropy and a loss of cellular identity
Radiation and environmental damage to DNA causes multiple negative long-term health outcomes
Permanence Bio is developing therapeutics that act at the root of disease
Preventing genome instability would lead to the prevention of cancer, a slowing of the onset of neurological diseases, and cures for patients with numerous genetic diseases
Protecting the genome can save the lives of those exposed to radiation and chemical hazards
Our approach incorporates artificial intelligence to drive a high-throughput screening platform for the discovery of genome-stabilizing therapies
Our team is deeply passionate about the mission
We aspire to make a meaningful change in the world by changing how we think about disease: prioritizing the prevention of core drivers of illness
We are advised by many of the world’s experts in cancer prevention, medicinal chemistry, and longevity